Quantitative evaluation using the plaque/muscle ratio index panels predicts plaque type and risk of embolism in patients undergoing carotid artery stenting.

نویسندگان

  • Koichiro Takemoto
  • Tetsuya Ueba
  • Koichi Takano
  • Hiroshi Abe
  • Yoko Hirata
  • Toshio Higashi
  • Tooru Inoue
  • Noriyuki Sakata
  • Kengo Yoshimitsu
چکیده

OBJECTIVE We sought to use a magnetic resonance (MR) plaque imaging technique to establish the plaque/muscle ratio (PMR) index panel to identify vulnerable plaques in subjects undergoing carotid artery stenting (CAS). METHODS Between 2008 and 2010 we treated 69 patients (71 lesions) by elective carotid endarterectomy (CEA) and 35 patients (36 lesions) by CAS. All patients underwent preoperative MR plaque imaging and the ratio of plaque signal intensity to the sternocleidomastoid muscle was calculated. In the CEA group, we categorized the histopathological findings made on the surgical specimens. In the CAS group, we assessed the post-procedure diffusion-weighted images. RESULTS PMR index panels for each plaque type were created using the cut-off value obtained from the receiver operating characteristic (ROC) curves of each plaque type. The probability of each of the four plaque types on each panel was assessed by Fisher's exact test. Multinomial logistic regression analysis of the DWI-positive findings determined significant probability (p=0.042). CONCLUSION The results of this study suggest quantitative evaluation using the PMR index panel has a probability to predict both the plaque type and risk of embolism in patients being considered for treatment with CAS.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

High-risk plaque for carotid artery stenting evaluated with 3-dimensional T1-weighted gradient echo sequence.

BACKGROUND AND PURPOSE Preventing cerebral embolisms is a major concern with carotid artery stenting (CAS). This study evaluated 3-dimensional T1-weighted gradient echo (3D T1GRE) sequence to predict cerebral embolism related to CAS. METHODS We performed quantitative analyses of the characteristics of 47 carotid plaques before CAS by measuring the signal intensity ratio (SIR) and plaque volum...

متن کامل

Atherosclerotic plaque vulnerability as an explanation for the increased risk of stroke in elderly undergoing carotid artery stenting.

BACKGROUND AND PURPOSE Recent randomized trials showed an increased periprocedural risk for stroke with increasing age in patients undergoing carotid artery stenting. Manipulation of atherosclerotic plaques during carotid artery stenting can result in plaque rupture with subsequent superimposed thrombus formation, embolization, and cerebrovascular events. We hypothesized that atherosclerotic pl...

متن کامل

Branch retinal artery occlusion following carotid stenting: A case report.

A 70 year old male was diagnosed with carotid stenosis and underwent carotid artery stenting (CAS). Severe postoperative complications arose subsequent to the procedure, including decreased visual acuity and symptoms of a visual field defect, and the patient was eventually diagnosed with retinal artery embolism. CAS reduces carotid plaque; however, the subsequent shedding of carotid plaque may ...

متن کامل

Systemic atherosclerotic plaque vulnerability in patients with Coronary Artery Disease with a single Whole Body [FDG]PET-CT scan

Objective(s): Cardiovascular disease is a leading cause of morbimortality with over half cardiovascular events occurring in the asymptomatic population by traditional risk stratification. This preliminary study aimed to evaluate systemic plaque vulnerability in patients with prior Coronary Artery Disease (CAD) with a single Whole Body [FDG] PET-CT scan in terms of plaq...

متن کامل

Carotid doppler ultrasound evaluation in patients with lichen planus

Background: Lichen planus is a chronic inflammatory disease associated with an increased risk of subclinical atherosclerosis and cardiovascular diseases. This study aimed to evaluate patients with lichen planus using carotid Doppler ultrasound parameters.Methods: Forty patients with lichen planus and 40 controls were included in this study. Common carotid...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Clinical neurology and neurosurgery

دوره 115 8  شماره 

صفحات  -

تاریخ انتشار 2013